A logistics company has deployed a hybrid environment that has multiple VPCs in both the us-east-1 Region and the af-south-1 Region. The on-premises data center is connected to us-east-1 through an AWS Direct Connect connection. The Direct Connect connection is connected to a Direct Connect gateway that is associated with a transit gateway. The transit gateway is attached to all the VPCs in us-east-1.
An application that is deployed in af-south-1 requires access to a database in the data center. The application also requires access to file storage in a VPC in us-east-1.
Which solution will meet these requirements with the LOWEST latency?

A. Create a transit gateway in af-south-1, and attach the VPCs. Create a transit gateway peering connection between the transit gateways.
B. Create a Direct Connect connection in af-south-1, and attach the VPCs with a Direct Connect gateway and a transit gateway. Create an AWS Site-to-Site VPN connection over the internet between the Direct Connect connections.
C. Create a transit gateway in af-south-1, and attach the VPCs. Associate the transit gateway in af-south-1 with the Direct Connect gateway in us-east-1.
D. Create inter-Region VPC peering connections between the VPCs in each Region. Use the transit gateway attachments in us-east-1 to access the database in the data center.